bs-82963C
[Life Science]
NS 1619
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
NS 1619 is a selective activator of large conductance Ca(2+)-dependent potassium channels (BKCa or KCa1.1).1,2 It was able to increase blood-brain tumor barrier permeability in rat brain tumor models.3,4 NS 1619 inhibited proliferation and induced apoptosis in A2780 ovarian cancer cells.5 Displays cardioprotective effects in an ischemia-reperfusion model6 and neuroprotective effects in a traumatic brain injury model7.
Description:
CAS Number: 153587-01-0<br></br>Chemical Name: 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole-2(3H)-one<br></br>Molecular weight: 362.23<br></br>Formula: C15H8F6N2O2<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.