DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Potent HSP90 inhibitor (IC50 = 30 nM HER-2 degradation).1 It inhibited the proliferation of MCF7 and BT474 breast cancer cell lines (IC50 = 100 nM for each). BIIB021 has shown efficacy as a therapeutic in multiple cancer models.2-5
Description:
CAS Number: 848695-25-0<br></br>Chemical Name: 6-Chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]purin-2-amine<br></br>Molecular weight: 318.76<br></br>Formula: C14H15ClN6O<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)