DATASHEET
Formulation
Yellow oil
Storage:
-20°C
Product Information:
RIPA-56 is a potent (IC50 = 13 nM, EC50 = 28nM for HT-29 cells) and selective inhibitor of Receptor-Interacting Protein 1 (RIP1) kinase with significant metabolic stability (t1/2 = 128min human liver microsomal stability assay). RIPA-56 showed excellent kinase selectivity and did not inhibit IDO at 200 µM.
Description:
CAS Number: 1956370-21-0<br></br>Chemical Name: N-Benzyl-N-hydroxy-2,2-dimethylbutanamide<br></br>Molecular weight: 221.30<br></br>Formula: C13H19NO2<br></br>Solubility: DMSO (>50 mg/ml) Ethanol (>50 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)