DATASHEET
Formulation
Pale yellow solid
Storage:
-20°C
Product Information:
N-Acetyl-S-farnesyl-L-cysteine (AFC) inhibits S-farnesylcysteine methyl transferase (Km = 20 µM).1 AFC blocked capacitative Ca2+ influx in human embryonic kidney 293 cells2 and store-regulated Ca2+ entry in human platelets3. Topical AFC has been shown to inhibit neutrophil chemotaxis and other inflammatory responses without systemic effects.4,5
Description:
CAS Number: 135304-07-3<br></br>Chemical Name: 2-Acetamido-3-(3,7,11-trimethyldodeca-2,6,10-trienylsulfanyl)propanoic acid<br></br>Molecular weight: 367.55<br></br>Formula: C20H33NO3S<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Yellow oil<br></br>Purity: 98% by TLC, NMR (Conforms)