DATASHEET
Formulation
Tan Solid
Storage:
-20°C
Product Information:
Rbin-1 is potent (GI50 = 136 nM) and reversible inhibitor of eukaryotic ribosome assembly. The biochemical target of Rbin-1 is Midasin (Mdn1), an essential AAA+ protein. Blocking of Mdn1 by Rbin-1 inhibits the processing of pre-60S particles, important pre-ribosomal subunits produced in the nucleolus.
Description:
CAS Number: 328023-11-6<br></br>Chemical Name: 3-[(2-Methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole<br></br>Molecular weight: 256.33<br></br>Formula: C13H12N4S<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: >98% by TLC, NMR (Conforms)