bs-82927C
[Life Science]
gamma-L-Glutamyl-p-nitroanilide HCl
DATASHEET
Formulation white solid
Storage: -20°C
Product Information:
L-γ-Glutamyl-p-nitroanilide (GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5)2 Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3
Description:
CAS Number: 67953-08-6<br></br>Chemical Name: <br></br>Molecular weight: 303.70<br></br>Formula: C11H13N3O5 · HCl<br></br>Solubility: Water (5 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98%
Size: 100 mg, 250 mg100 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.