bs-82924C
[Life Science]
TTFA
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
TTFA blocks the respiratory chain complex II causing inhibition of mitochondrial respiration. Respiratory chain complex II inhibition is caused via binding of TTFA to two ubiquinone binding sites, Qp and Qd.1 Inhibition of Complex II by TFA has been shown to cause a delay in overall cell cycle progression leading to oxidative stress.2,3 TTFA also was found to inhibit porcine liver carboxylesterase (IC50 = 0.54 µM).4
Description:
CAS Number: 326-91-0<br></br>Chemical Name: Thenoyltrifluoroacetone; 4,4,4-Trifluoro-1-(2-thienyl)-1,3-butanedione<br></br>Molecular weight: 222.18<br></br>Formula: C8H5F3O2S<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: >98%, NMR (Conforms)
Size: 100 mg, 500 mg100 mg, 500 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.