bs-82921C [Life Science]
BML283
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Formulation Off-white solid

Storage: -20°C

Product Information:

BML283 is a selective activator of the Tumor Specific M2 Isoform of Pyruvate Kinase (PKM2) - AC50 = 111nM.1 PKM2 activity is downregulated in most cancer cells leading to a decrease in catabolic metabolism and an increase in anabolic metabolism.2,3 BML283 is an important tool for studying the effects of PKM2 and cancer metabolism.

Description:

CAS Number: 562867-96-3<br></br>Chemical Name: 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)piperazine<br></br>Molecular weight: 454.51<br></br>Formula: C19H22N2O7S2<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: white solid<br></br>Purity: 98% by TLC, NMR (Conforms)

Size: 5 mg, 25 mg5 mg, 25 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.