bs-82916C
[Life Science]
Mitoguazone · 2HCl
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Mitoguazone is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC).1,2 SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism.3 Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase.4,5 Mitoguazone has been looked at as a potential anti-cancer treatment because of it’s ability to inhibit polyamine synthesis.6
Description:
CAS Number: 31959-87-2<br></br>Chemical Name: Methylglyoxal bis(guanylhydrazone) dihydrochloride<br></br>Molecular weight: 257.13<br></br>Formula: C5H12N8 · 2HCl<br></br>Solubility: water (>25 mg/ml) DMSO (?)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC, NMR (Confirms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.