bs-82912C
[Life Science]
RepSox
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
RepSox is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-β type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4
Description:
CAS Number: 446859-33-2<br></br>Chemical Name: 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine; E-616452; SNJ 2511<br></br>Molecular weight: 287.32<br></br>Formula: C17H13N5<br></br>Solubility: DMSO (>25 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 99% by HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.