bs-82904C
[Life Science]
7alpha-Hydroxycholesterol
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Metabolite resulting from the action of cholesterol 7 alpha-hydroxylase on cholesterol. 7α-Hydroxycholesterol is the first intermediate and a rate-limiting step in the major pathway for bile acid synthesis in humans. A pro-inflammatory mediator which upregulates production of CCL2 and MMP9 in macrophages and may promote progression of atherosclerosis.2,3 Possible biomarker for cellular lipid peroxidation.4
Description:
CAS Number: 566-26-7<br></br>Chemical Name: 5-Cholesten-3β, 7α-diol<br></br>Molecular weight: 402.66<br></br>Formula: C27H46O2 <br></br>Solubility: DMSO or Ethanol<br></br>Physical Properties: White or pale yellow solid<br></br>Purity: 98% by TLC [3:2 ethyl acetate : hexane; Rf = 0.15] NMR (Conforms)
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.