DATASHEET
Formulation
Solid
Storage:
-20°C
Product Information:
CPTH2 is a selective inhibitor of the histone acetyltransferase Gcn5P both in vitro and in vivo (IC50 = 0.8 mM). In vitro, the HAT inhibitory activity of CPTH2 was caused via bridge-interaction with histone H3. It’s in vivo activity may involve more histonic and/or non-histonic Gcn5p substrates.
Description:
CAS Number: 357649-93-5<br></br>Chemical Name: Cyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl]hydrazone<br></br>Molecular weight: 291.80<br></br>Formula: C14H14ClN3S<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC [10% ethyl acetate in hexanes / Rf: 0.32] NMR (Conforms)