bs-82889C
[Life Science]
GW1100
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
Selective antagonist of GPR40. GW1100 inhibits GRP40-mediated Ca2+ increases stimulated GW9508 or linoleic acid (pIC50 = 5.99 for either agonist).1 The effects of GPR40 activation on insulin secretion in cells are also blocked by the addition of GW1100.
GW1100 does not influence calcium mobilization mediated by GPR120.
Description:
CAS Number: 305974-70-9<br></br>Chemical Name: 1-(4-Ethoxycarbonylphenyl-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone<br></br>Molecular weight: 520.59<br></br>Formula: C27H25FN4O4S<br></br>Solubility: DMF (5 mg/ml) DMSO (2 mg/ml<br></br>Physical Properties: White solid<br></br>Purity: 96% by LCMS NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.