DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Inhibitor of FGFR tyrosine kinase, and to a lesser extent VEGFR1 (IC50 values are 5 nM, 22.5 nM and 100 nM for FGFR1, FGFR3 and VEGFR respectively). Inhibition of FGFR promotes stem sell self renewal.2,3
Description:
CAS Number: 219580-11-7<br></br>Chemical Name: 1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea<br></br>Molecular weight: 523.67<br></br>Formula: C28H41N7O3<br></br>Solubility: DMSO<br></br>Physical Properties: Yellow solid<br></br>Purity: 99% by HPLC, NMR (Conforms)