DATASHEET
Formulation
White to off-white solid
Storage:
-20°C
Product Information:
Potent (AC50 = 29 nM PKR; 37 nM PKM2; 33 nM PKL) allosteric activator of pyruvate kinase.1 In clinical use for the treatment of hemolytic anemia2 and a potential agent for the treatment for ß-thalassemia3 and sickle cell anemia4.
Description:
CAS Number: 1260075-17-9<br></br>Chemical Name: N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide<br></br>Molecular weight: 450.56<br></br>Formula: C24H26N4O3S<br></br>Solubility: DMSO (>50 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 99% by HPLC NMR (Conforms)