bs-82863C
[Life Science]
Epalrestat
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Epalrestat is an aldose reductase inhibitor (IC50 = 10 nM (rat lens) and 25 nM (human placenta).1,2 It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.3
Description:
CAS Number: 82159-09-9<br></br>Chemical Name: 2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid<br></br>Molecular weight: 319.40<br></br>Formula: C15H13NO3S2<br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >98% (TLC: 5% Methanol/methylene chloride + 0.5% HOAc; Rf = 0.21)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.