DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
TH257 is a potent (IC50’s = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.
Description:
CAS Number: 2244678-29-1<br></br>Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide<br></br>Molecular weight: 422.54<br></br>Formula: C24H26N2O3S<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White to off-white glassy solid<br></br>Purity: >98% by HPLC NMR (Conforms)