bs-82854C
[Life Science]
SLF1081851
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
SLF1081851 is a sphingosine-1-phosphate transporter (Spns2) inhibitor. It inhibited sphingosine-1-phosphate (S1P) release in HeLa cells: IC50 = 1.93 µM. SLF1081851 is active in vivo and decreased lymphocyte counts and plasma S1P levels in mice and rats. Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
Description:
CAS Number: 2763730-97-6 (free base)<br></br>Chemical Name: 3-(3-(4-Decylphenyl)-1,2,4-oxadiazol-5-yl)propan-1-amine hydrochloride<br></br>Molecular weight: 379.79<br></br>Formula: C21H33N3O·HCl<br></br>Solubility: DMSO (30 mg/ml) Ethanol (7 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.