DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Lomerizine is a clinically useful calcium channel blocker (L and T-type). It is used for the treatment of migraine headaches, however its antimigraine effects are believed to be due to its 5HT2A antagonistic effects.1 Lomerizine also displays anti-glaucoma effects via an increase in ocular circulation and protection of neuronal cells against retinal neurotoxicity with minimal cardiovascular effects.2 Lomerizine has also shown various other neuroprotective properties.3,4,5,6
Description:
CAS Number: 101477-54-7<br></br>Chemical Name: 1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride<br></br>Molecular weight: 541.46<br></br>Formula: C27H30F2N2O3·2HCl <br></br>Solubility: DMSO (>45 mg/ml) and Ethanol (30 mg/mL)<br></br>Physical Properties: White solid<br></br>Purity: >98% by TLC, NMR (Conforms)