DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Potent, selective, and cell permeable inhibitor of the BRD9 bromodomain, a subunit of the switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex (IC50 = 75 nM).1 It displayed antitumor activity in an acute myeloid leukemia xenograft model. BI-9564 displayed cytotoxic and anti-proliferative effects in 5 rhabdoid tumor cell lines.2
Description:
CAS Number: 1883429-22-8<br></br>Chemical Name: 4-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridine-1-one<br></br>Molecular weight: 353.42<br></br>Formula: C20H23N3O3 <br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC, NMR (Conforms)