bs-82840C
[Life Science]
ERGi-USU
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
Description:
CAS Number: 1147-56-4<br></br>Chemical Name: 1-(2-Thiazolylazo)-2-naphthol<br></br>Molecular weight: 255.30<br></br>Formula: C13H9N3OS<br></br>Solubility: DMSO (>10 mg/ml)<br></br>Physical Properties: Red or Orange solid<br></br>Purity: 98% by TLC NMR (Confirms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.