bs-82832C
[Life Science]
CGP-37157
DATASHEET
Formulation Off-white solid
Storage: RT
Product Information:
Inhibits the mitochondrial Na+-Ca2+ exchanger (NCX) in isolated heart mitochondria, IC50=0.36 μM.1 Does not inhibit the plasmalemmal NCX.2 Also inhibits voltage-gated Ca2+ channels in intact cells and therefore its use in cellular studies must employ adequate controls.3 Prevents sudden death in a Guinea pig model of heart failure.4 Displays pronounced cytoprotective effects in chromaffin cells5 and in neuronal injury models.6 Blood-brain barrier permeant.
Description:
CAS Number: 75450-34-9<br></br>Chemical Name: 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one<br></br>Molecular weight: 324.22<br></br>Formula: C15H11Cl2NOS<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by TLC
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.