DATASHEET
Formulation
Pale yellow solid
Storage:
-20°C
Product Information:
Spastazoline in as ATP-competitive inhibitor (IC50 = 99 nM) of the microtubule-severing AAA protein spastin. It is selective against four related AAA proteins (XL-katarin, Hs-FIGL1, Mm-VCP, and Hs-PCH2). A new and interesting tool for the study of the assembly, disassembly, or maintenance of microtubule-based cellular structures.
Description:
CAS Number: 2351882-11-4<br></br>Chemical Name: N-(5-tert-Butyl-1H-pyrazol-3-yl)-2-[(3R)-3-propan-2-ylpiperazin-1-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine<br></br>Molecular weight: 382.52<br></br>Formula: C20H30N8<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)