bs-82826C
[Life Science]
BD1063 dihydrochloride
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
BD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM).1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated µ-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.
Description:
CAS Number: 206996-13-6<br></br>Chemical Name: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride<br></br>Molecular weight: 346.13<br></br>Formula: C13H18Cl2N2·2HCl<br></br>Solubility: Water (>25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.