bs-82820C
[Life Science]
NE-100
DATASHEET
Formulation Pale pink/purple solid
Storage: -20°C
Product Information:
NE-100 is potent inhibitor of the sigma receptor () with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
Description:
CAS Number: 149409-57-4<br></br>Chemical Name: 4-Methoxy-3-(2-phenylethoxy)-N,N,dipropylbenzeneethanamine hydrochloride<br></br>Molecular weight: 391.97<br></br>Formula: C23H33NO2·HCl<br></br>Solubility: DMSO (>25 mg/ml) Water (10 mg/ml) <br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.