bs-82814C
[Life Science]
GSK2636771
DATASHEET
Formulation Off-white to pale pink solid
Storage: -20°C
Product Information:
GSK2636771 is a potent, selective (>1000-fold over α, 10-fold over δ, and >2000-fold over γ), and orally bioavailable inhibitor of PI3Kß (IC50 = 5.2 nM).1 Active in vitro against multiple types of PTEN-deficient cancer cells. GSK2636771 potently blocked migration and invasion of DU145 prostate cancer cells.2 GSK2636771 has also been identified as a GPR39 agonist.3
Description:
CAS Number: 1372540-25-4<br></br>Chemical Name: 2-Methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid<br></br>Molecular weight: 433.43<br></br>Formula: C22H22F3N3O3<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.