bs-82813C
[Life Science]
Gilteritinib
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Potent inhibitor of FLT3 (IC50 = 5 nM, wild-type FLT3) with more potent activity against all FLT3 mutants.1 It also potently inhibits Axl (IC50 = 41 nM). Clinically useful in the treatment of acute myeloid leukemia. Gilteritinib has also been shown to inhibit glutamine uptake and utilization via downregulation of glutamine transporters.2
Description:
CAS Number: 1254053-43-4<br></br>Chemical Name: 6-Ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide<br></br>Molecular weight: 552.72<br></br>Formula: C29H44N8O3<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Off-white to pale pink solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.