DATASHEET
Formulation
Orange solid
Storage:
-20°C
Product Information:
H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.
Description:
CAS Number: 941987-60-6<br></br>Chemical Name: N-(4-Ethylphenyl)-N’-1H-indol-3-yl urea<br></br>Molecular weight: 279.34<br></br>Formula: C17H17N3O<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98%, NMR (Conforms)