bs-82788C
[Life Science]
TIC10
DATASHEET
Formulation Off-white to beige solid
Storage: -20°C
Product Information:
TIC10 (1616632-77-9) is novel anti-cancer compound that acts via early-stage integrated stress response activation leading to selective cancer cell death.1-3 TIC10 potently activates mitochondrial caseinolytic protease P (ClpP) causing eIF2-independent induction of ATF4 and Akt/ERK/Foxo3a/DR5/TRAIL-dependent apoptosis.4 Currently in clinical trials.
Description:
CAS Number: 1616632-77-9<br></br>Chemical Name: 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one<br></br>Molecular weight: 386.49<br></br>Formula: C24H26N4O<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 98% by TLC
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.