DATASHEET
Formulation
Pale yellow solid
Storage:
-20°C
Product Information:
Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer’s disease.3
Description:
CAS Number: 112887-68-0<br></br>Chemical Name: (2S)-2-[[5-[Methyl-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid<br></br>Molecular weight: 458.49<br></br>Formula: C21H22N4O6S<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: >98% by HPLC NMR (Conforms)