bs-82777C
[Life Science]
GSK620
DATASHEET
Formulation Off-white to beige solid
Storage: -20°C
Product Information:
BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).
Description:
CAS Number: 2088410-46-0<br></br>Chemical Name: 1-Benzyl-5-N-cyclopropyl-3-N-methyl-2-oxopyridine-3,5-dicarboxamide<br></br>Molecular weight: 325.37<br></br>Formula: C18H19N3O3<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.