bs-82776C
[Life Science]
SGC-iMLLT
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Potent (IC50 = 260 nM) inhibitor of the YEATS domain of MLLT1/3.1 YEATS domain containing proteins bind acetyl and crotonyl marks on histone tails. Selective against the two other human YEATS domains YEATS2/4 and 48 bromodomains. YEATS containing MLL-ENL leukemic cells display increased sensitivity to SGC-iMLLT versus control AML cells.2
Description:
CAS Number: 2255338-25-9<br></br>Chemical Name: (S)-1-Methyl-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazole-5-yl)-1H-indazole-5-carboxamide<br></br>Molecular weight: 388.48<br></br>Formula: C22H24N6O<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Off-white to beige solid<br></br>Purity: >98% HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.