bs-82772C
[Life Science]
PFI-3
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
PFI-3 (1819363-80-8) is a selective inhibitor of family VIII bromodomains PB1(5), SMARCA2, and SMARCA4.1 It showed complete selectivity over all non-family VIII bromodomains. PFI-3 blocked adipogenesis in C3H10T1/2 mesenchymal cells at 20µM.Treatment of embryonic stem cells with PFI-3 led to deprivation of stemness and deregulated lineage specificity. Differentiation of trophoblast stem cells in the presence of PFI-3 was enhanced.2 Cell permeable.
Description:
CAS Number: 1819363-80-8<br></br>Chemical Name: (2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridine-2-yl)-2,5-diazabicyclo{2.2.1]heptan-2-yl]prop-2-en-1-one<br></br>Molecular weight: 321.37<br></br>Formula: C19H19N3O2<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98%, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.