DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pathway signaling in MCF7 cells by altering YAP nuclear localization in a SETD7-dependent manner.
Description:
CAS Number: 1627607-87-7<br></br>Chemical Name: (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride<br></br>Molecular weight: 535.98<br></br>Formula: C23H25F4N3O3S HCl<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC NMR (Conforms)