DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
EPZ015666 is a selective and potent (IC50 = 22nM) inhibitor of arginine methyltransferase 5 (PRMT5).1,2 PRMT5 inhibition with EPZ015666 potently suppressed in vivo glioblastoma tumors3 and significantly inhibited the growth of multiple myeloma cell lines4.
Description:
CAS Number: 1616391-65-1<br></br>Chemical Name: (S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide<br></br>Molecular weight: 383.44<br></br>Formula: C20H25N5O3<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (conforms)