bs-82763C
[Life Science]
EED-226
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
EED-226 is a potent (IC50 = 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repressive complex 2 (PRC2).1,2 It caused drastic proliferation inhibition in lymphoma cells with EZH2 mutations and caused shrinkage and slower tumor growth in mice using a subcutaneous xenograft model of Karpas422.
Description:
CAS Number: 2083627-02-3<br></br>Chemical Name: N-(Furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolol[4,3-c)pyrimidine-5-amine<br></br>Molecular weight: 369.40<br></br>Formula: C17H15N5O3S<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.