bs-82759C
[Life Science]
Lomeguatrib
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.
Description:
CAS Number: 192441-08-0<br></br>Chemical Name: 2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purine<br></br>Molecular weight: 326.17<br></br>Formula: C10H8BrN5O3S <br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Off-white or beige solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.