bs-82751C
[Life Science]
MPEP HCl
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5).1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinson’s3,4, Fragile X syndrome5, and addiction6.
Description:
CAS Number: 219911-35-0<br></br>Chemical Name: 2-Methyl-6-(2-phenylethynyl)pyridine hydrochloride<br></br>Molecular weight: 229.71<br></br>Formula: C14H11N·HCl <br></br>Solubility: DMSO (20 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: White or pale yellow solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.