bs-82736C
[Life Science]
EN450
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1
Description:
CAS Number: 793719-01-4<br></br>Chemical Name: N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide<br></br>Molecular weight: 288.75<br></br>Formula: C11H13ClN2O3S<br></br>Solubility: DMSO (>80 mg/ml)<br></br>Physical Properties: White to off-white solid<br></br>Purity: >98% by HPLC , NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.