bs-82727C
[Life Science]
BIBR1532
DATASHEET
Formulation Orange waxy solid
Storage: -20°C
Product Information:
Non-competitive specific inhibitor of telomerase (IC50 = 93 nM), targeting telomerase reverse transcriptase (hTERT).1,2 Induces apoptosis in MCF-7 breast cancer cells and breast cancer stem cells3 and affected the epithelial mesenchymal transition in breast cancer stem cells4. BIBR1532 eliminated pancreatic stem cells via DNA damage and apoptosis in primary patient-derived samples.5 It significantly inhibited cell proliferation and induced apoptosis in acute myeloid leukemia stem cells.6
Description:
CAS Number: 321674-73-1<br></br>Chemical Name: (E)-2-(3-(Naphthalen-2-yl)but-2-enamido)benzoic acid<br></br>Molecular weight: 331.37<br></br>Formula: C21H17NO3<br></br>Solubility: DMSO (up to 50 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.