bs-82716C
[Life Science]
JNJ-63533054
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Potent and selective brain-penetrant GPR139 agonist (EC50=16 nM) an orphan G-protein-coupled receptor expressed in the CNS.1 Tritium-labeled JNJ-63533054 binds to cell membranes expressing GPR139 and can be displaced by putative endogenous ligands.2 Decreases compulsive-like alcohol drinking and hyperalgesia in alcohol-dependent rodents.3 Suppresses morphine intake in a mouse self-administration model.4
Description:
CAS Number: 1802326-66-4<br></br>Chemical Name: (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl) benzamide<br></br>Molecular weight: 316.78<br></br>Formula: C17H17ClN2O2 <br></br>Solubility: DMSO (35 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC NMr (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.