bs-82704C [Life Science]
Ranolazine
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DATASHEET

Formulation Colorless film

Storage: RT

Product Information:

Ranolazine is an FDA-approved drug used for the treatment of chronic angina. It inhibits the late inward sodium current in heart muscle leading to decreased intracellular calcium levels.1 It blocks Nav 1.4, 1.5, 1.7 and 1.8 (IC50’s = 2.42, 6.22, 1.72(10.33), 21.53 µM respectively.

Description:

CAS Number: 142387-99-3<br></br>Chemical Name: (±)-N-(2,6-Dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)-propyl]piperazin-1-yl]acetamide<br></br>Molecular weight: 427.54<br></br>Formula: C24H33N3O4<br></br>Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC (10% methanol/methylene chloride; Rf = 0.63)

Size: 10 mg, 50 mg10 mg, 50 mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.