DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
A highly potent and selective inhibitor of HDAC2 isolated from the Panamanian marine cyanobacterium cf. Symploca (IC50=0.119 and 434 nM for HDAC2 and HDAC6 respectively).1 Induces apoptosis and cancer cell death only in combination with other HDAC1 inhibitors.2 Potential therapeutic agent for breast cancer.3 Attenuates A fragment (A25-35)-induced toxicity in PC12 cells by enhancing ER stress tolerance.4 Ameliorates Alzheimer’s disease-like pathology in mouse models.4
Description:
CAS Number: 1477949-42-0<br></br>Chemical Name: N-[4-Oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester<br></br>Molecular weight: 278.35<br></br>Formula: C15H22N2O3 <br></br>Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)