bs-82686C
[Life Science]
Allopregnanolone
DATASHEET
Formulation Black solid
Storage: -20°C
Product Information:
Endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approved (Brexanolone) for postpartum depression.3 Inhibits TLR4 receptor activation and inflammatory signaling in macrophages and brain.4 Inhibits glutamate release5 and displays neuroprotective effects in various animal models6.
Description:
CAS Number: 516-54-1<br></br>Chemical Name: (3α,5α)-3-Hydroxy-pregnan-20-one<br></br>Molecular weight: 318.49<br></br>Formula: C21H34O2 <br></br>Solubility: DMSO (32 mg/ml) Ethanol (32 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.