bs-82683C
[Life Science]
Autophinib
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Inhibits autophagy induced by starvation or rapamycin by inhibiting the lipid kinase VPS34 (IC50=19 nM).1 Increased autophagy and apoptosis were rescued by autophinib in Per1-overexpressing oral squamous cell carcinoma cells.2 Autophinib has quickly become an important biochemical tool for inhibition of autophagy in a variety of cellular contexts.3-5
Description:
CAS Number: 1644443-47-9<br></br>Chemical Name: 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-4-pyrimidinamine<br></br>Molecular weight: 346.73<br></br>Formula: C14H11ClN6O3<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.