bs-82680C
[Life Science]
TPPU
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
Description:
CAS Number: 1222780-33-7<br></br>Chemical Name: N-[1-(1-Oxopropyl)-4-piperidinyl]-N’-[4-trifluoromethoxy)phenyl]urea<br></br>Molecular weight: 359.35<br></br>Formula: C16H20F3N3O3<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: >98% by HPLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.