bs-82679C
[Life Science]
Napabucasin
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of stemness-high cancer cells isolated from a variety of cancer types.1 Effective antitumor agent as a monotherapy or in combination with other agents such as taxol in mouse models.2 Clinical trials have demonstrated encouraging anti-tumor activity with the potential to suppress metastasis and prevent relapse in patients with various types of cancer.2,3 Overcomes cisplatin resistance in non-small cell lung cancer.4
Description:
CAS Number: 83280-65-3<br></br>Chemical Name: 2-Acetylnsphtho[2,3-b]furan-4,9-dione<br></br>Molecular weight: 240.21<br></br>Formula: C14H8O4<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.