bs-82678C
[Life Science]
α-Mangostin
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
α-Mangostin is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.2 Induces IFN- production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells.5
Description:
CAS Number: 6147-11-1<br></br>Chemical Name: 1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one<br></br>Molecular weight: 410.46<br></br>Formula: C24H26O6 <br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.