bs-82675C
[Life Science]
VGX1027
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Immunomodulator. Inhibits secretion of IL-1β, TNF-α, and IL-10 from murine macrophages stimulated with LPS and spares T cell function.1 Ameliorates the course of acute and chronic immunoinflammatory conditions such as carrageenan-induced pleurisy, LPS-induced lethality and type II collagen-induced arthritis in mouse models.1 Prevents spontaneous and accelerated forms of autoimmune diabetes in a NOD mouse model.2 Moldulates genes involved in LPS-induced Toll-like receptor 4 activation in a mouse Lupus model.3 Displays protective effects in particulate matter-induced acute lung injury by blocking TLR4 signaling.4
Description:
CAS Number: 6501-72-0<br></br>Chemical Name: 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid<br></br>Molecular weight: 205.2<br></br>Formula: C11H11NO3<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.