DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4
Description:
CAS Number: 571203-78-6<br></br>Chemical Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone<br></br>Molecular weight: 547.04<br></br>Formula: C30H31ClN4O4<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC, NMR (Conforms)